Aspirin is a non-steroidal drug with a wide spectrum of effects. It is used not only for pain or fever, but also for diseases of the cardiovascular system. However, this tool has a number of contraindications, and before you start using it, you should read the instructions.

Composition, release forms and packaging

The main component of Aspirin is acetylsalicylic acid.

The medication is available in the following forms:

  • classic tablets 0 1 g;
  • effervescent tablets 0.5 g;
  • soluble powder, packaged in bags.

In classic Aspirin tablets, only the main component is present, while effervescent ones are made with the addition of corn starch and microcrystals of cellulose.

In addition to acetylsalicylic acid, the powder contains the following substances:

  • citric acid;
  • NaHCO3;
  • flavors and colorants.

The medicine is dispensed by a network of pharmacies without a prescription and is suitable for use for 5 years. Keep the packaging in a dry place inaccessible to children, away from sunlight.

Pharmacological action, pharmacodynamics and pharmacokinetics

Aspirin helps reduce pain, and also eases the patient's condition with fever accompanying colds, flu, and other disorders. In addition, the drug can reduce the severity of symptoms in diseases in the acute and chronic form, characterized by inflammatory processes, and helps to maintain normal platelet count.

Acetylsalicylic acid is easily absorbed into the blood through the walls of the stomach, after which it transforms into salicylic acid. The substance is rapidly distributed to organs and cells, and is metabolized in the liver. The components of the drug are excreted mainly with urine.

What helps Aspirin

What is good about Aspirin is its ability to quickly bring relief in disorders associated with pain, inflammation and fever.

It is used in the treatment of such manifestations:

  • headaches and toothaches;
  • colds and flu, accompanied by fever and sore throat;
  • aches in joints and muscles;
  • infectious and inflammatory processes;
  • disorders in the functioning of the cardiovascular system;
  • cerebrovascular accident;
  • in the prevention of thrombosis (to "thin" the blood).

In addition, Aspirin is prescribed in the postoperative period, after coronary artery bypass grafting.

Instructions for use and dosage

When using Aspirin in tablets, it is recommended to calculate a single dose from 0.5 to 1 g. In this case, the maximum volume per day for adults should not be more than 3 g. Repeated use of the drug is possible no less than 4 hours after the previous one.

If a powder composition is used in the treatment of the disease, you need to drink it one at a time three to four times a day. In this case, the interval between taking the medicine should be at least 6-8 hours.

The duration of the treatment course is discussed with the doctor individually, depending on the nature of the disease. As a rule, Aspirin is used for no more than 3 days as a remedy for temperature and fever, and in other cases up to 5 days.

Attention! In accordance with generally accepted recommendations on how to take Aspirin, it should not be given to patients under the age of 15 in order to avoid disturbances in the liver. But in some cases, it can be used under strict medical supervision. In such a situation, the recommended daily dose is from 1 to 3 g.

During pregnancy and lactation

Treatment with aspirin during pregnancy is contraindicated. In the first trimester, it can lead to splitting of the upper palate, and in the third trimester, it can provoke a delay in labor and various metabolic disturbances in the fetus.

From the third to the sixth month of gestation, a single intake of aspirin is possible only in connection with a special need, when other drugs can not bring relief.

Acetylsalicylic acid is able to pass into breast milk, so it is not recommended to drink Aspirin during lactation. Due to its effects in the child's body, disorders associated with platelet function may occur.

Can I drink alcohol while taking Aspirin?

Like many medicinal formulations, Aspirin is incompatible with alcoholic beverages. The fact is that both individually acetylsalicylic acid and ethanol are aggressive substances, and when interacting, these properties are enhanced.

If you take Aspirin tablets in combination with alcohol or other formulations containing ethanol compounds, the risk of damage to the mucous membranes in the digestive tract increases. This threatens with various disorders in the functioning of the digestive organs, and in especially severe cases - bleeding.

Drug interaction

If Aspirin is prescribed to the patient, but at the same time he takes other medications, you need to notify the attending physician about this. This medication is incompatible with some groups of drugs, so its features should be considered.

When combined with medicinal compositions containing magnesium or aluminum hydroxides, the absorption of acetylsalicylic acid is impaired. This helps to reduce the effectiveness of the drug.

The active component of the drug, in turn, is able to reduce the effects of drugs of the uricosuric and antihypertensive groups, as well as diuretics.

In the treatment with acetylsalicylic acid, the toxic effect on the body is enhanced if the patient additionally takes drugs such as:

  • narcotic analgesics;
  • other nonsteroids;
  • hypoglycemic drugs;
  • indirect anticoagulants;
  • thrombolytics;
  • formulations with methotrexate and heparin.

The combination of Aspirin with glucocorticosteroids threatens with the same manifestations as with a combination with alcohol or alcohol-containing compounds.

Contraindications, side effects and overdose

For all its effectiveness and speed of exposure, Aspirin can cause significant damage to the body. This is due to the fact that the drug contains aggressive components.

Its use is prohibited in the following conditions:

  • bronchial asthma, developed due to the use of certain medications;
  • hemarrhagic diathesis;
  • ulcerative lesions of the gastrointestinal tract in the acute stage;
  • increased susceptibility to the active components of the composition;
  • during pregnancy and breastfeeding;
  • under the age of 15 years.

Precautions should be observed in cases where Aspirin is prescribed to a patient suffering from the following diseases:

  • gout
  • bronchial asthma;
  • gastrointestinal ulcer;
  • polyps in the nasal cavity;
  • pathological processes in the respiratory organs, both acute and chronic;
  • disorders in the liver and kidneys;
  • hyperuricemia.

Attention! Despite the fact that Aspirin is contraindicated during pregnancy, it can be prescribed in connection with certain violations to women in the second trimester. But in this case, the drug is used only once.

The following disorders are noted as side effects from the use of the drug:

  • stomach pains;
  • the appearance of skin rashes;
  • periodic spasms in the bronchi;
  • imbalance of platelets.

When taking the drug for a long time, the risk of developing such conditions is high:

  • thrombocytosis;
  • myocardial dystrophy;
  • dysbiosis;
  • micronutrient metabolic disorders;
  • the formation of stones in the urinary tract;
  • endocrine disorders, up to diabetes;
  • anemia and leukocytosis;
  • red blood cell imbalance;
  • renal failure and other disorders in the work of the body.

In some cases, with incorrect use of Aspirin, gastric bleeding occurs.

This severe violation is accompanied by the following symptoms:

  • stool disorders;
  • severe pain and pain in the stomach;
  • anemia and general weakness.

This condition requires urgent medical attention, so if you see signs of bleeding, you should immediately call an ambulance.

An overdose of Aspirin is accompanied by the following symptoms:

  • headache;
  • tinnitus;
  • nausea and vomiting
  • dizziness
  • impaired perception and weakening of reactions to external stimuli;
  • confusion or loss of consciousness.

In severe forms of intoxication, in addition to the listed symptoms, the following also occur:

  • body temperature rises;
  • breathing quickens, as a result of which a larger volume of air enters the lungs than is necessary;
  • as a result of an excess of oxygen, respiratory alkalosis and respiratory failure develops;
  • heart function is disturbed, up to the development of cardiogenic shock;
  • sharply reduced blood sugar, due to which hypoglycemia occurs;
  • carbohydrate starvation occurs, thereby provoking the development of ketosis;
  • an imbalance of substances in the blood occurs, which leads to metabolic acidosis;
  • in especially severe cases, a coma develops.

In this condition, the patient needs urgent hospitalization. In a hospital, emergency measures will be taken and symptomatic treatment given.

Analogues of the drug

There are many drugs similar to Aspirin in the active substance.

If necessary, you can replace this drug with such medicines:

  • Anopyrine;
  • ASK cardio;
  • Aspicore;
  • Asinatom;
  • Acecardolol;
  • Acenterinum;
  • Acylpyrine;
  • Atsbirinom;
  • Bufferin;
  • Zorex;
  • Colpharitis;
  • Mikristinom;
  • Taspir;
  • Thrombopol;
  • Walsh asalgin;
  • Upsarin UPSA.

When using Aspirin or its analogues, it is important to understand that acetylsalicylic acid is far from harmless. This aggressive component is capable of provoking serious disorders in the work of the body if the dosage or the regimen is violated. But with proper use, the drug leads to the development of side effects and unwanted symptoms extremely rarely.

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