There are many vitamin complexes in pharmaceuticals, but Milgamma is suitable for the neurological field, because it contains the most optimal set of microelements that make it possible to establish neural connections.

Composition and form of release

Medical statistics show the significant effectiveness of taking B vitamins in neurology. This is due to the fact that the preparations containing them have an analgesic effect, improve blood circulation and normalize the functioning of the central nervous system. Due to this, they are often prescribed by neurologists as an adjuvant for the treatment of CNS pathologies and problems with the musculoskeletal system.

The vitamin product "Milgamma" is available in three forms: in the form of tablets, dragees and injection solution.

  • The liquid format of the drug is made in ampoules with a volume equal to a single dose of the drug (2 ml). The ampoules are brown in color, made of hydrolytic glass. Each has a manufacturer's stamp. The solution is available in packs of 5 and 10 capsules.
  • Milgamma tablets are sold in boxes containing 30 or 60 pieces of a vitamin product, coated to facilitate swallowing.
  • Along with Milgamma tablets, the manufacturer also produces Compositum tablets.They have the appearance of a biconvex white circle enclosed in cell packaging. One blister contains 15 tablets. The drug is sold in an amount of 30 or 60 doses.

The composition of the two indicated formats is not identical.

So the composition of the solution includes:

  • 100 mg pyridoxine and thiamine hydrochloride;
  • benzyl alcohol;
  • sodium hydroxide;
  • cyanocobalamin;
  • sodium polyphosphate;
  • lidocaine.

The list of components included in the tablet form of "Milgamma" is much narrower:

  • thiamine;
  • pyridoxine;
  • glycerides;
  • crystallized cellulose;
  • povidone;
  • talc and other excipients.

Thus, the saturation with useful elements in the solution is higher. However, the choice of one form or another of the drug should be carried out only by a specialist who is able to take into account all the individual characteristics of the patient's body.

Pharmacological action, pharmacodynamics and pharmacokinetics

Due to the fact that the basis of the drug is vitamins of group B, most often it is prescribed to normalize the functioning of nerve impulses. Thanks to it, amino acids are produced that help optimize metabolic processes.

Vitamin B6 promotes the formation of histamine, adrenaline, and dopamine. The pharmacodynamics of the pills and injections "Milgamma" is excellent.

  • So, after oral administration, benfotiamine is actively absorbed, the concentration of which reaches a maximum after 50 minutes.
  • In the case of intramuscular injection of the Milgamma solution, absorption of active substances into the blood occurs almost instantly. Once in the general bloodstream, pyridoxine binds to plasma proteins, and then is absorbed by brain tissue. After 2 hours, the drug is excreted through the urogenital system.

What are prescribed injections and pills Milgamma

Medical practice has proven the effectiveness of the drug, but by itself, he will not be able to get rid of any ailment. It should be taken in combination with other means.

Taking the drug is advisable with:

  • rehabilitation after surgery or previous serious illnesses;
  • muscle pain and cramps;
  • alcohol and diabetic polyneuropathy;
  • vitamin deficiency;
  • neuralgia;
  • multiple sclerosis;
  • plexopathy;
  • radiculitis;
  • osteochondrosis;
  • neuritis (retrobulbar);
  • ganglionitis;
  • lumbago;
  • paresis of the facial nerve.

The medicine effectively fights herpes zoster and other similar infections caused by viruses that damage the nervous system. Recently, Milgamma is often used in cosmetology to improve the structure of the skin and hair.

For the treatment of neuralgic symptoms, Milgamma injections are indicated. If the purpose of the intake is to normalize the content of vitamin B in the body, then it is more advisable to use a tablet form of the drug.

Instructions for use of B vitamins in ampoules and tablets

The regularity of taking the drug is determined by the severity of the disease and is determined by the attending physician. As a rule, Milgamma Compositum tablets are taken orally after meals with a frequency of three times a day. To facilitate digestibility, the drug must be washed down with plenty of drinking water. When the regressive stage of the disease occurs, the doctor can reduce the dosage of the drug to a single dose. The maximum duration of use is 1 month.

Instructions for use of the solution:

  1. For the treatment of the progressive stage of pathology, B vitamins in ampoules are prescribed in an amount of 2 ml, which corresponds to one ampoule. The drug is administered intramuscularly 1 time in 24 hours. The time of day does not play a role.
  2. After eliminating most of the symptoms of the disease, the patient is transferred to light therapy, in which the frequency of injections is reduced to 2 to 3 times per week.

The duration of use of the solution "Milgamma" is 2 weeks. Exceeding the specified period is not recommended, becausethis will cause a general deterioration in well-being and the occurrence of side effects of the drug.

During pregnancy and lactation

The medicine is rapidly absorbed into the bloodstream and easily penetrates the placental barrier. In view of this, in order not to harm the unborn child, the use of Milgamma during gestation is strictly contraindicated. Studies of the degree of influence of the components of the drug on the child have not been conducted, so taking the drug is justified only if there is a serious threat to the life of the mother.

During lactation, the use of the drug is also not advisable, because it freely penetrates into milk.

Drug interaction

Specialists do not recommend combining Milgamma with other medicines on their own. In the best case, the effect of therapy will be nullified, in the worst, the normal functioning of the heart and liver will be disrupted.

The drug should not be combined with the following agents:

  • magnesia;
  • aseptics containing mercury chloride;
  • means, which include potassium iodide;
  • sedatives based on lithium carbonate;
  • glucose and riboflavin;
  • medicines containing esters, tannic and acetic acids;
  • antioxidant and additive E381.

The effectiveness of Milgamma may decrease due to changes in the alkaline balance in the patient’s body.

At the same time, there are drugs that, when used in combination with them, the beneficial effect of Milgamma is greatly enhanced.

These include:

  • Diclofenac
  • Movalis
  • Midokalm.

However, in any case, only a specialist can prescribe complex therapy, based on data on the patient’s health status.

Compatibility of injections, tablets Milgamma with alcohol

Milgamma, like other medicines, is not compatible with alcohol. The parallel use of B vitamins and alcohol-containing products provokes overexcitation of the central nervous system, which results in an exacerbation of the disease and increased symptoms.

Contraindications, side effects and overdose

The medicine has a number of contraindications.

So, it is forbidden to take in cases:

  • hypersensitivity to allergic reactions;
  • the presence of violations in the rhythm of the heart and vascular conduction in the acute phase;
  • detecting an increased number of red blood cells in the blood;
  • hypersensitivity to the components that make up the product;
  • diagnosing thromboembolism;
  • gastric and duodenal ulcers;
  • chronic decompensated heart failure;
  • as well as during pregnancy and lactation;
  • and in childhood (up to 14 years).

The instructions for use of the drug describe in detail the dosage of the drug. Its excess several times increases the likelihood of a patient having an adverse reaction to the drug.

At the same time, even with the correct use of Milgamma, in rare cases, an unusual reaction of the body may appear in the form of:

  • urticaria;
  • swelling and itching;
  • digestive tract disorders;
  • anaphylactic shock.

Similar manifestations are characteristic of the tablet form of Milgamma.

Possible side effects from injections are slightly different:

  • allergic skin rashes;
  • dyspepsia;
  • tachycardia;
  • acne;
  • increased sweating;
  • spasms of the calf muscles.

If these symptoms appear after starting to use the drug, you should inform your healthcare provider about this to resolve the issue of replacing the drug with another.

Analogs of vitamin B group in injections and tablets

Due to its special popularity, Milgamma has a number of analogues of different price segments.

Most Popular:

  • "Combilipen";
  • "Neurobion";
  • Vitagamma
  • "Neuromultivitis."

According to statistics, most often "Milgamma" is replaced by "Combipilene", because it is a domestic analogue of a drug, the cost of which is significantly cheaper.

It contains the same B vitamins and lidocaine, but in a reduced concentration.

Another domestic drug is Vitagamma. It is considered an analogue of the injectable solution of Milgamma. The composition and principle of the two agents are almost identical. Only the price of the first is an order of magnitude lower.

"Neuromultivit" is an Austrian vitamin complex. Its recognized merit is the rare occurrence of adverse reactions. As a rule, it is prescribed to reduce pain during pathologies of the nervous system.

Neurobion has a different composition from Milgamma, but is also popular in the Russian market. It also contains thiamine, pyridoxine, cyanocobalamin, but in a different concentration.

There are other, less well-known analogues of the drug. However, you should not try to replace one drug with another on your own, because only a specialist can know all the subtleties and rules of combining medicines.

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