One of the means of choice for eliminating acute pain is Nimesil powder. This drug has a good short-term effect, but is dangerous because of the potential occurrence of many side effects. The best recommendation in this case is the refusal to self-prescribe potent drugs.
Material Content:
The composition of the drug
The bag contains small granules for suspension. The taste of the drink is improved due to the orange flavor, sweetener and citric acid. To maintain the structure of the suspension, the macrogol polymer and maltodextrin are added to the powder.
The main active ingredient is nimesulide. A portion prepared from one sachet contains 0.1 g of this component.
Pharmacological properties and indications for use
When answering the question why Nimesil helps, it should be said right away that it does not have a therapeutic effect - they drink the suspension as an anesthetic.
It removes sensations in the following conditions:
- joint pain
- pain during the menstrual cycle;
- acute muscle pain, including after injuries and sprains;
- pain due to inflammation of the teeth and gums.
The active ingredient blocks receptors that are sensitive to pain mediators.
As a result, when inflammatory agents are thrown into the intercellular space, the nerve endings simply cease to perceive them. The thrill is suppressed, the pain gradually subsides.
In addition, the same component acts in a different direction - it reduces the production of substances formed during inflammation. Thus, not only the pain syndrome subsides, but also redness, swelling, and swelling of the tissues pass.
Age restrictions on admission
Powder for oral administration is prohibited for children under twelve years of age due to its high toxicity.
Nimesil powder: instructions for use
This substance is potent. Its incorrect dosage can have far-reaching negative consequences. You can reduce the likelihood of adverse reactions by reducing the duration of admission.
How to breed Nimesil powder
Granules dissolve best in warm water. They are placed in a glass and filled with a hundred milliliters of liquid. The prepared product is not stored, but consumed immediately.
Dosage regimen
The contents of one package are used once. This is a standard one-time rate. Everyone, starting at the age of twelve, is prescribed the same dosage.
At most, you can take Nimesil in an amount of not more than two sachets. The course of treatment should not exceed twelve days.
In order to avoid the occurrence of side effects, you should try to minimize the daily intake of the drug and the duration of the entire treatment.
Special instructions for use
- During prolonged use of the drug, it is necessary to monitor the condition of the kidneys and blood picture.
- In patients with gastrointestinal diseases, exacerbation of problems may occur during administration. At the first appearance of signs of intoxication and digestive upset, further treatment should be abandoned.
- In patients with impaired renal and hepatic function, individual correction of the norm of admission is required. For the elderly, such measures are not provided.
Eating does not affect the degree of absorption of the active substance. But in order to avoid complications from the digestive tract, the prepared suspension must be drunk after eating.
In practice, cases of sharp visual impairment during treatment were recorded. If you have any problems with the eyes, you should stop taking the powder.
If during the treatment period the body temperature rises or respiratory infections occur, further use of the drug should be discarded.
Drug Interactions with Other Drugs
- The active substance partially inhibits platelet production and promotes blood thinning. Its use is contraindicated with the simultaneous administration of drugs that perform the same function. Violation of these requirements is fraught with the discovery of internal bleeding.
- Powder is able to reduce the effectiveness of diuretics and prevent the removal of salts from the body.
- The drug enhances the toxicity of antibiotics and antitumor drugs. Their simultaneous administration has a destructive effect on the liver. For the same reason, the suspension is not compatible with alcohol.
- With the simultaneous use of powder and vasodilators that lower blood pressure, enzymes that suppress the activity of the kidneys can accumulate. As a result, renal failure develops as a side effect.
- The active substance argues with drugs against diabetes. For this reason, their joint reception is unacceptable.
Contraindications, side effects
The drug in question has an impressive list of contraindications.
Its use is canceled if, in the past and present, the patient had or continues to have:
- inflammatory diseases of any part of the digestive tract, complicated by ulcers, erosion, perforation of the wall, bleeding;
- serious violations in the work of the excretory system;
- pathological conditions of the liver;
- poor susceptibility of non-steroidal pain medications;
- aspirin poisoning;
- allergy to other anti-inflammatory drugs;
- pathology of the hematopoietic system with coagulation;
- any hay fever, sinusitis, respiratory disease;
- fever;
- body temperature that differs from normal;
- surgical intervention in the work of the heart and blood vessels;
- hypertension, diabetes mellitus of the second type;
- pregnancy and lactation period.
A separate line of contraindications should highlight alcoholism and smoking. The drug has a strong effect on the liver. It should not be prescribed to those who have ever undergone chemical organ destruction in the past.
Among the reactions to the substance are observed:
- allergies, dermatitis of varying severity up to tissue rejection;
- violations of the blood picture with a sharp decrease in the number of red blood cells and an increase in inflammation and an allergic reaction;
- decreased visual acuity;
- changes in the work of the heart with a rhythm disturbance, a change in blood pressure;
- nervous seizures, dizziness, decreased performance, impaired brain function, a feeling of fear at night;
- respiratory distress;
- general malaise;
- exacerbation of intestinal diseases;
- urinary retention;
- weakening of the liver and kidneys;
This list does not include individual reactions to the drug.
Analogs of Nimesil
The analogues of the suspension include drugs:
- Aponil;
- Nise
- "Nimegesic";
- "Nimesulide";
- "Nimid";
- Nimulide.
Basically, the analogues are drugs of Indian origin, which at a price win against the powder in question. All drugs from the list have the same active substance, so they have similar instructions for use. Medicines are dosed according to one principle.
- Aponil is produced in Cyprus. Has a dosage form of tablets. In the unit of the drug 100 mg of the active substance. Like all medicines of this series, it is dispensed by prescription.
- “Nise” is produced in the form of half and whole dose tablets. Also available as an external 1% gel. In the case of the gel, you must not exceed the allowable ten-day course of treatment. In this form, the drug can be applied only to undamaged skin.
- "Nimegesic" - a finished suspension with the aroma of ripe melon. It is used in adults. One-time rate - two caps. 60 ml of medicine is placed in a bottle.
- "Nimesulide" - 100 mg tablets. Rarely in pharmacies is sold in gel form. It is applied similarly to Nise.
- "Nimid" is a product of Indian origin in the form of sachets and external gel. Dosages and method of use are exactly the same as for similar drugs.
- Nimulide is an Indian counterpart. It occurs in tablets, in the form of an external gel and a finished suspension. It was previously recommended to children as the most powerful antipyretic. Later it turned out that the reception is not compatible with high temperature.
Now all drugs based on such an active substance are prohibited for children under 12 years of age.
The powder in question has a pronounced analgesic property. Reviews about its use are mostly positive. But do not forget that this tool greatly complicates the work of the liver. Therefore, whenever possible, long-term treatment should be avoided.
