Detralex is a French-made drug that has a venotonic and angioprotective effect. It is prescribed for the treatment of patients with hemorrhoids and venous insufficiency. In our article you will find a description of Detralex tablets, a guide to their use and a list of effective substitutes.
Material Content:
The composition of the drug
The drug is available in the form of tablets. Detralex contains a purified flavonoid fraction (90 percent diosmin and 10 percent hesperidin). This fraction is the main substance of the drug.
Pharmacological properties and pharmacokinetics
Detralex is a capillary stabilizing medicine.
He is able to cure:
- impaired blood circulation;
- capillary extensibility;
- venous congestion.
In addition, Detralex stimulates lymphatic outflow, increases vascular resistance and tones veins.
Under the influence of pharmaceuticals in vessels, the elasticity and extensibility decreases, hemodynamics improve. The drug does not allow white blood cells to stick to the walls of the endothelium, which minimizes the risk of damage to the vascular valve flaps.
Since the active component of Detralex underwent micronization, it is more actively distributed throughout the body, has a quicker and deeper therapeutic effect. The patient feels relief after taking two tablets (1000 mg).
The bulk of Detralex comes out with feces. About 14 percent are present in urine. The drug eliminates half-life in eleven hours.Detralex undergoes an active metabolism.
Indications for use of tablets Detralex
It is advisable to prescribe a medication to eliminate the symptoms of venolymphatic insufficiency (pain and heaviness in the legs, nightly convulsive lesions, swelling, trophic disorders and varicose ulcers). Also, this pharmaceutical tool has proven itself against acute and chronic hemorrhoids.
Against acute hemorrhoids, Detralex is usually prescribed in combination with symptomatic topical drugs.
Detralex is often prescribed against localized edema. It is used before and after surgery to reduce venous insufficiency.
How to take the drug
Instructions for use states that the drug is intended for oral use. The tablet should be swallowed completely and washed down with water. It is forbidden to dissolve and grind with teeth. Detralex is taken with meals.
Patients with venous-lymphatic disease need to take one tablet 2 times a day: the first is better to drink closer to dinner, the second - in the evening.
Detralex tablets for hemorrhoids should be taken according to this scheme: six tablets per day for four days in a row. The patient must drink 3 tablets in the morning, the remaining 3 - in the evening. Further, the dose is reduced to four tablets per day. The daily dose is also divided into two doses and is used according to the scheme described above.
With exacerbation of hemorrhoids, Detralex will not be able to treat existing anal disorders. If at the end of the therapeutic course the patient does not feel relief, he needs to urgently visit a doctor. The specialist must examine the patient and develop a new treatment regimen for him.
The use of Detralex should not exceed the periods prescribed in the instructions.
During pregnancy and lactation
Studies have shown that Detralex does not adversely affect the fetus. At the moment, there are no officially registered cases that expectant mothers complained about the development of side effects while taking the drug.
It is forbidden to be treated with Detralex during lactation, because there is no information confirming / refuting its ability to penetrate into breast milk.
It has been experimentally proven that the drug does not affect fertility.
Drug Interactions with Other Drugs
The combination of Detralex with medicines has not been tested. However, the patient is obliged to notify the attending physician of all drugs that are taking at the time of prescribing this medication.
Contraindications, side effects and overdose
Despite its high effectiveness, the drug cannot be prescribed to all patients. It is not recommended to prescribe to patients suffering from hypersensitivity to any component of Detralex.
Detralex 500 mg tablets are generally well tolerated by patients. However, in some patients, certain side effects were observed during treatment.
These include:
- In the digestive tract: diarrhea (frequent and loose stools), nausea, heartburn, pain in the abdomen, inflammation of the large intestine.
- On the skin: rashes, itching, hyperemia, irritation, urticaria, angioedema, anaphylactic shock.
Very rarely, patients complained of headaches, vertigo and general malaise.
There are no officially registered cases of overdose Detralex.
Patients who abused the drug noted that they began to be disturbed:
- bouts of nausea;
- gagging;
- violation of the stool;
- dyspeptic symptoms.
With the development of such conditions, you need to urgently seek qualified medical help. As a rule, in such cases, symptomatic therapy is performed.
Detralex analogs tablets
Since this drug is considered relatively expensive, many patients ask the doctor to choose an effective substitute. We bring to your attention a brief description of the popular Detralex analogues.
Troxerutin
The medication is based on the active ingredient of the same name. Presented as ointment. Since Troxerutin has a completely different composition, for the treatment of varicose veins it can be used only by medical prescription.
Troxevasin
A drug for external use, based on troxerutin. It has a venotonic, venoprotective, decongestant and anti-inflammatory effect. Prescribed for the treatment of dilated veins and capillaries in the legs. Helps reduce the negative effects of bruises, sprains, and injuries.
Venozol
This Detralex analogue in tablets is still considered the cheapest. The composition of Venozol has five active components. Pharmaceuticals effectively cope with varicose veins, swelling of the lower extremities. Before use, it is recommended that you familiarize yourself with the list of contraindications and side effects.
Venoruton
The drug is presented in the form of a gel for local use. It effectively copes with chronic venous insufficiency. Venoruton does not have the same composition as Detralex, so it is difficult to say whether it will be as effective. It can be used only as directed by a doctor.
Diosmin
This medication has a pronounced venotonic and angioprotective effect. It effectively copes with peripheral venous insufficiency and hemorrhoids. Based on the active component of the same name. Prohibited for the treatment of patients under the age of eighteen, pregnant and lactating women.
Phlebaven
Detralex Oral Tablets. Diosmin and hesperidin are also present in its composition.
Helps eliminate:
- a feeling of heaviness in the limbs;
- pain and fatigue in the legs;
- acute hemorrhoids.
Phlebodia 600
This drug has a similar cost. The French drug is based on diosmin. He is prescribed against acute hemorrhoids and severe pain in the lower extremities. Flebodia 600 is contraindicated in children under 18 years of age, women in the first trimester of pregnancy and nursing mothers.
Venus
Domestic angioprotector and venotonic. It is produced in the form of tablets. It has the same active components as Detralex. Venarus helps patients overcome venous insufficiency and chronic hemorrhoids. Only in extreme cases, it is prescribed during the period of bearing the child and feeding. Venarus has an extensive list of contraindications, so it should be drunk exclusively as prescribed by a specialist.
Antistax
Swiss encapsulated medication that helps cure varicose veins, swelling of the legs, remove burning sensation and fatigue in the legs. It differs from Detralex in composition, but is no less effective. Prohibited for use by pregnant and lactating women.
Despite the good effectiveness of Detralex, it can only be used for the appointment of a specialist. Otherwise, it can greatly aggravate the patient's health.
