"Vizanna" is a pharmaceutical agent widely used by specialists in obstetrics and gynecology. The basis of the drug is dienogest, which is characterized by a strong gestagenic effect, which reduces the activity of estrogen. In our article, instructions on the use of "Vizanna" and a list of its effective substitutes are given.

Release form and composition of the drug

The drug "Vizanne" is represented by round-shaped tablets of white, even without interspersed color. One of the sides is framed with an engraving “B”. The blister packs up 14 tablets. In a cardboard pack can be from two to twelve blisters.

The active component of the pharmaceutical is dienogest. Each tablet contains 2 mg of the main substance.

Pharmacological effect and indications for use

Dienogest, the main component of Vizanne, is able to:

  • reduce the total number of nerve endings in areas of endometriosis, which ensures a decrease in pain intensity;
  • reduce inflammation;
  • inhibit the production of prostaglandins that cause pain;
  • stop the increase in the mucous layer;
  • normalize hormonal levels by inhibiting estrogen production;
  • to deplete the vessels that feed the endometrium.

Vizann tablets are not able to affect the egg. Because of this, women planning to give birth do not need to worry that the drug will negatively affect their health.

Doctors say that in patients experiencing difficulties with conception, pregnancy after "Byzantine" came much easier.

The drug is prescribed for:

  • endometriosis therapy;
  • reduce large bleeding and menstrual pain;
  • conception planning.

Dienogest can be used as an independent medicine and as a component of complex treatment. To achieve the maximum therapeutic effect, "Vizanne" must be taken according to the instructions.

The agent under discussion can harm patients in whom:

  • breast cancer
  • there is a neoplasm or there is reason to suspect it;
  • swelling in the liver (even in the anamnesis);
  • vaginal bleeding of unclear nature;
  • intolerance to the components of "Byzantine";
  • lactase deficiency;
  • heart and arterial problems;
  • flowing venous thromboembolism;
  • any type of diabetes.

In extreme cases, "Vizanne" should be assigned to women with:

  • Depression
  • increased blood pressure;
  • chronic heart failure;
  • hyperlipidemia;
  • migraine

Also at risk are patients who have had an ectopic pregnancy.

Instructions for use and dosage of Vizann

The official instructions for the drug say that you need to drink it for six months. The right to decide whether to continue therapy is best left to the attending physician.

The beginning of the use of "Byzantine" does not depend on the female cycle.

On the day you need to drink 1 tablet of the medication, which if necessary can be washed down with water. It is advisable to drink the medicine at one time. When one pack of pills ends, you need to immediately start a new one.

If a medication is missed or vomiting or diarrhea has begun within 3 hours after its administration, the effectiveness of the therapy is reduced. To compensate for the non-absorbed dose due to digestive upset, you can additionally drink another tablet of “Byzanne”.

If you missed the time of taking during the day, you need to drink the drug at every opportunity, but the next day to take the medicine at the usual time.

Side effects, overdose

Most patients tolerate Vizanne well, but for some, its administration may be accompanied by:

  1. From the circulatory system: anemia, impaired blood circulation, palpitations, decreased blood pressure.
  2. From the sensory organs: a feeling of drying out eyes, phantom ringing in the head.
  3. From the genitourinary system: breast enlargement, chest pain, periodic bleeding from the uterus, ovarian cysts, vaginal candidiasis, discharge, pelvic pain, vulvovaginitis, infectious infection.
  4. On the skin: itching, pathological hair loss, dermatitis, impaired pigmentation, light intolerance, hypertrichosis.
  5. From the side of the central nervous system: headaches, migraines, emotional leaps, depression, anxiety.
  6. From the digestive tract: bouts of nausea, vomiting, epigastric pain, bloating, upset stool, gingivitis.
  7. Other: weight reduction / increase, swelling, irritability, fatigue.

As a rule, side effects disappear within a few days after the start of treatment with Vizannaya.

So far, there is no data on the serious consequences caused by an overdose of the drug.

High doses may be accompanied by:

  • nausea
  • vomiting
  • uterine discharge.

Overdose therapy is symptomatic.

Drug Interactions with Other Drugs

The level of dienogest in the body and the likelihood of side effects increase if “Vizanne” is combined with grapefruit juice and inhibitors:

  • "Itraconazole";
  • "Ketoconazole";
  • Verapamil
  • Cimetidine
  • Erythromycin
  • Clarithromycin
  • "Ritonavir"
  • Indinavir
  • "Fluoxetine."

The clearance of sex hormones is increased and the therapeutic effect of "Byzanne" is reduced, if you combine it with:

  • barbiturates;
  • "Carbamazepine"
  • "Rifamzipin"
  • Nevirapin
  • means with St. John's wort in the composition.

Pregnancy and lactation

Information on the use of "Byzantine" by expectant mothers is limited.The results of studies on the use of dienogest by pregnant women showed that this substance does not adversely affect pregnancy, fetal development, the birth process and the subsequent development of the baby.

"Vizanne" is not prescribed for pregnant women, since during this period there is no need to treat endometriosis.

Appointment in the lactation period is contraindicated, since the drug together with breast milk can enter the body of the baby. If a woman urgently needs to be treated with Vizannaya, it is better to transfer the child to artificial nutrition.

special instructions

The official manual says that "Vizanne" does not affect psychomotor reactions and the ability to concentrate.

When treating the drug under discussion, it is forbidden to drink OK.

Before the start of therapy for endometriosis, conception should be excluded, since this disease is not treated during pregnancy.

When using medications, you must definitely inform your doctor about this before starting treatment with Vizannaya.

Menstruation after completion of treatment begins within a few months. This phenomenon is quite normal, because during this time the body recovers from the hormonal effects of the drug.

Vizanne and alcohol are compatible. During treatment, dry wine (150 ml) and fortified (70 ml) are allowed.

Analogs

This medication does not have full analogues in the active component. But on the pharmaceutical market there are combined products containing 2 mg of dienogest. These drugs are oral contraceptives, the main task of which is to suppress ovulation to prevent conception.

If Vizanna is often prescribed for endometriosis, then OK is not specifically used against this disease. But if for some reason a woman cannot take the drug in question, she is picked up an analogue from the OK list. One of the main differences between these medicines is the specificity of the reception. "Vizanne" needs to drink courses, OK - constantly. It should also be borne in mind that estrogens are present in the composition of the latter, so it is difficult to predict how they will affect endometriosis.

The same estrogens as part of combined medications can provoke serious negative reactions that are not characteristic of Vizanne. Long-term use of OK can be accompanied by thrombosis and metabolic disorders. Therefore, the pharmaceuticals of this group have more contraindications.

Analogs for the active substance:

  • Bonade. Product of the Czech pharmaceutical company Zentiva. The average cost of a monthly course of treatment is 520 rubles.
  • "Janine." German company Bayer. A 21-day course will cost 950 rubles.
  • "Dicyclylene". The drug is available in the Netherlands and Spain. The price of pack No. 21 is 600 rubles.
  • "Genetten." German drug with a composition similar to the above medicines. It rarely appears in our pharmacies.
  • "Siluet." Hungarian medicine from Gedeon Richter. For packaging number 21, you can pay more than 620 rubles.
  • "Climodien." This German OK contains 2 mg of estradiol valerate. Packaging number 28 will cost more than 3500 rubles.
  • Klaira. Another German remedy, similar in composition to climodiene. For a monthly course of treatment you will have to pay more than 900 rubles.

In addition to the combined OK, "Vizanne" can be replaced:

  • Mirena;
  • "Veraplex";
  • Megeys;
  • Norkolutom;
  • Dufaston.

To get a good result, you need to take gestagens for a long time. As a rule, the dosages of drugs are very high, so you need to strictly monitor your health and, in the slightest development of side effects, immediately seek medical help.

To date, "Vizanne" is considered the only medication that helps cure endometriosis. There is no identical analogue of this drug yet. The relatively high price of the drug is fully offset by its therapeutic effect.

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